AIs as they accumulate knowledge and data across a large number of fields including science, finance, social, business, governance will change everything in ways no one can imagine or predict due to the broad range of its uses and ability to accelerate literally everything at the same time. Never has man had to deal with so many variables changing so fast. If we don't learn how to harness this great power, we could be in for multiple conflicting disasters that we can't even imagine. Now is the time to put safeties and guidelines in place before we walk into a disaster and instead reap untold riches and benefits. Any thoughts, comments or suggestions sought. Now is the time to start considering the impact of AI/ML that is now upon us.